54(4), 2007, pp.1033-1039

A Clean Synthesis of 1,4-Diarylquinoline Derivatives Catalyzed by TEBAC in Aqueous Media

Xiang-Shan Wang*, Mei-Mei Zhang, Hong Jiang, Da-Qing Shia, and Shu-Jiang Tua

Department of Chemistry, Xuzhou Normal University, Xuzhou Jiangsu 221116, P. R. China

Abstract.     A series of 1,4-diarylquinoline derivatives were synthesized by the reaction of arylmethylidenemalononitriles or 2-cyano-3-aryl-1-acrylate and 3-arylamino-5,5-dimethylcyclohex-2-enone in aqueous media at 100 °C catalyzed by TEBAC. Meanwhile, the water medium was chosen as green solvent.

Keyword:  Quinoline; TEBAC; Aqueous media; Synthesis.